​A method for assessing the toxicological potentials of product systems in a life cycle perspective

The ProScale method is currently further developed to make it operational and accessible to a large number of users via online tools and an extensive database covering basic chemicals. 
For more information : contact@proscale.org
(Guidance document, Excel tool (BETA version),
2017 ProScale Conference material)
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About ProScale

What is ProScale?

ProScale is a method providing a hazard and exposure based scoring system for comparing chemical risks associated with products in a life cycle perspective.



ProScale was initiated in 2016 by a consortium of 7 partners, with the aim of providing companies across the industrial value chain with a reliable tool enabling them to address stakeholders' requests to provide toxicological information on the chemicals used in their product systems.

ProScale offers a performance based indicator that can consolidate hazard and direct exposure potentials from chemicals along their life cycle, that can be applied and communicated within Life Cycle Analysis ("LCAs"), Environmental Product Declarations (“EPDs”) and Product Environmental Footprints (“PEFs”) by

  1. using life cycle thinking,

  2. using a risk-based approach for product assessments,

  3. aggregating from single product to a complete product solution and

  4. using existing, systematic data


Current status/Next steps

  • Phase I of ProScale, focusing on human toxicological aspects, was completed in 2017.  The method is presented in the ProScale Guidance Document


  • Implementation of Phase I of ProScale -  2018 (ongoing, and open to external contributions)

    • development of an online database platform

    • population of the database with data sets for ca. 200 basic chemicals

  • Initiation of Phase II of ProScale - 2019 (subject to prior scoping)

    • integrating ecotoxicological aspects in the ProScale scoring system


ProScale Consortium members

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ProScale ®

ProScale Consortium

c/o UetlibergPartners GmbH

Schindellegistrasse 71

CH - 8830 Pfäffikon

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Disclaimer: The ProScale method has been developed with a view to making it applicable worldwide in its intended use. However, the current version as defined in the ProScale Guidance Document is developed with the EU chemicals regulation as a starting point. The ProScale consortium acknowledges that other data sources may be available and relevant in other regions. Also, the ProScale consortium has not been able to check the accuracy of all data items provided in the Guidance, Annexes and other help files. For any particular case study applying ProScale, users are advised to check the accuracy of data used referring to the original data source. Under no circumstances can ProScale documents be used as reference documents in legal matters relating to chemical safety assessments or similar.

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  © 2017-2018  - ProScale is a registered Trade Mark of UetlibergPartners GmbH

on behalf of the ProScale consortium